Description: This product is a colorless to slightly yellow or yellowish green clear liquid.
Pharmacological Actions:Pharmacodynamics: Gentamicin is an aminoglycoside antibiotic that is resistant to a variety of Gram-negative bacteria (such as Escherichia coli, Klebsiella, Proteus, Pseudomonas aeruginosa, Pasteurella, Salmonella, etc.) and Staphylococcus aureus (Including strains producing β-lactamase) have antibacterial effects. Most cocci (Streptococcus pyogenes, Pneumococcus, Streptococcus faecalis, etc.), anaerobic bacteria (Bacteroides or Clostridium), Mycobacterium tuberculosis, Rickettsia and fungi are resistant to this product.
Pharmacokinetics: Absorption is rapid and complete after intramuscular injection. The peak plasma concentration is reached within 0.5 to 1 hour. The bioavailability of subcutaneous or intramuscular injection exceeds 90%. It is mainly excreted through glomerular filtration, and the excretion accounts for 40% to 80% of the dose. The elimination half-life after intramuscular injection is 1.8 to 3.3 hours for horses, 2.2 to 2.7 hours for calves, 0.5 to 1.5 hours for dogs and cats, 1 hour for cows and pigs, 1 to 2 hours for rabbits, sheep, buffalo, cattle and milk Goat is 2.3 to 3.2 hours.
Drug Interaction:
(1) The combination of gentamicin, tetracycline, erythromycin, etc. may have an antagonistic effect.
(2) Combined use with cephalosporin, dextran, strong diuretics (such as furosemide, etc.), erythromycin, etc., can enhance the ototoxicity of this product.
(3) Skeletal muscle relaxants (such as succinylcholine chloride, etc.) or drugs with such effects can enhance the neuromuscular blockade of this product.
Function and Use: Aminoglycoside antibiotics. Used for Gram-negative and positive bacterial infections.
Dosage and Administration: Intramuscular injection: one dose, per 1 kg body weight, 0.05~0.1ml for domestic animals; 0.075~0.125 ml for dogs and cats. Use it twice a day for 2 to 3 days.
Packaging and Delivery
Company Profile
FAQ:
Q1: Can you supply free samples?
A: Yes. We can provide with Free sample
Q2: How to assure your delivery same good quality as sample?
A: We just take sample from mass production. So same production line, same quality. Even we can supply you pre shipment batch sample approval.
Q3: How to assure our delivery and quality after prepayment? If there is a dispute about quality etc., how to solve the problem?
A: We are committed to ingredients industry over 10 years. Our products were hot sold to Asia, Oceania, Middle East, Europe, South America, North America and Africa. The producer we are collaborating were all on-site evaluated medium size enterprise with complete production management and quality control system.
Q4: What kind of payment do you prefer?
A: We can accept TT, D/P, D/A, L/C, West Union. For long term good-reputed clients, we also release open term.
Pharmacological Actions:Pharmacodynamics: Gentamicin is an aminoglycoside antibiotic that is resistant to a variety of Gram-negative bacteria (such as Escherichia coli, Klebsiella, Proteus, Pseudomonas aeruginosa, Pasteurella, Salmonella, etc.) and Staphylococcus aureus (Including strains producing β-lactamase) have antibacterial effects. Most cocci (Streptococcus pyogenes, Pneumococcus, Streptococcus faecalis, etc.), anaerobic bacteria (Bacteroides or Clostridium), Mycobacterium tuberculosis, Rickettsia and fungi are resistant to this product.
Pharmacokinetics: Absorption is rapid and complete after intramuscular injection. The peak plasma concentration is reached within 0.5 to 1 hour. The bioavailability of subcutaneous or intramuscular injection exceeds 90%. It is mainly excreted through glomerular filtration, and the excretion accounts for 40% to 80% of the dose. The elimination half-life after intramuscular injection is 1.8 to 3.3 hours for horses, 2.2 to 2.7 hours for calves, 0.5 to 1.5 hours for dogs and cats, 1 hour for cows and pigs, 1 to 2 hours for rabbits, sheep, buffalo, cattle and milk Goat is 2.3 to 3.2 hours.
| Product Name: | Gentamicin |
| CAS: | 1403-66-3 |
| MF: | C60H123N15O21 |
| MW: | 1390.71 |
| EINECS: | 215-765-8 |
| Gentamicin Chemical Properties | |
| Melting point | 102-108° |
| alpha | D25 +146° |
| pka | pKa 8.2(66% DMF) (Uncertain);7.9(H2O) (Uncertain) |
| CAS DataBase Reference | 1403-66-3(CAS DataBase Reference) |
| EPA Substance Registry System | Gentamicin(1403-66-3) |
Drug Interaction:
(1) The combination of gentamicin, tetracycline, erythromycin, etc. may have an antagonistic effect.
(2) Combined use with cephalosporin, dextran, strong diuretics (such as furosemide, etc.), erythromycin, etc., can enhance the ototoxicity of this product.
(3) Skeletal muscle relaxants (such as succinylcholine chloride, etc.) or drugs with such effects can enhance the neuromuscular blockade of this product.
Function and Use: Aminoglycoside antibiotics. Used for Gram-negative and positive bacterial infections.
Dosage and Administration: Intramuscular injection: one dose, per 1 kg body weight, 0.05~0.1ml for domestic animals; 0.075~0.125 ml for dogs and cats. Use it twice a day for 2 to 3 days.
Packaging and Delivery
Company Profile
FAQ:
Q1: Can you supply free samples?
A: Yes. We can provide with Free sample
Q2: How to assure your delivery same good quality as sample?
A: We just take sample from mass production. So same production line, same quality. Even we can supply you pre shipment batch sample approval.
Q3: How to assure our delivery and quality after prepayment? If there is a dispute about quality etc., how to solve the problem?
A: We are committed to ingredients industry over 10 years. Our products were hot sold to Asia, Oceania, Middle East, Europe, South America, North America and Africa. The producer we are collaborating were all on-site evaluated medium size enterprise with complete production management and quality control system.
Q4: What kind of payment do you prefer?
A: We can accept TT, D/P, D/A, L/C, West Union. For long term good-reputed clients, we also release open term.