Product Description
Name: Bromhexine hydrochloride
C.A.S NO. : 611-75-6
Synonyms: Bromhexine hcl
Molecular formula: C14H20BR2N2.HCL
Molecular weight : 412.59
Characteristic: White crystalline powder
Solubility: Slightly soluble in water, ethanol; soluble in hot ethanol; insoluble in acetone, chloroform.
Melting point: 237-238ºC
Certification of Analysis
ITEMS | STANDARD | RESULTS |
APPEARANCE | WHITE OR ALMOST WHITE CRYSTALLINE POWDER | ALMOST WHITE CRYSTALLINE POWDER |
IDENTIFICATION | COMPLIES | PASS |
RELATED SUBSTANCES | COMPLIES | PASS |
LOSS ON DRYING | ≤1.0% | 0.1% |
SULPHATED ASH | ≤0.1%
| 0.08% |
Assay | 98.5%~101.5% | 99.7% |
CONCLUSION | THE PRODUCT COMPLIES WITH PRESCRIBED STANDARD OF BP2005 |
Function&Application
Bromhexine hydrochloride is a medication prescribed for coughs which works by dissolving hard phlegm. This tends to be given to those with respiratory diseases who have difficulty coughing this out otherwise - by breaking it down it becomes smaller and easier to expel and this means they can breathe without their airways being blocked while also providing cough relief. It is preferable to some cough medication as it does not include any sedatives which can otherwise make those using the medication drowsy. At the same time many other cough medicines simply sooth the throat without actually breaking down the phlegm.
Bromhexine hydrochloride has direct effects on the bronchial glands, which promote the release of lysosomes in the mucus secretory cells, causing the dissociation of the sticky sugar fibers in the sputum;It can also inhibit the synthesis of acid glycoprotein in mucous glands and goblet cells, so as to secrete the small molecule glycoprotein with low viscosity, thus reducing the viscosity of sputum and making it easy to cough.In addition, it can stimulate the gastric mucosa reflex to increase the secretion of the respiratory glands and dilute sputum.
Bromhexine hydrochloride is usually to treat cute and chronic bronchitis, asthma, bronchiectasis, emphysema, especially suitable for the white sticky sputum cough and the severe acute disease caused by the widespread obstruction of small bronchi caused by sputum.
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Packing detail :
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